Cytochalasin C K-0518) 3 nM in BF-227 (Kd

3 nM in BF-227 (Kd value of [125I]BF-180: 10

resulting in aneuploidy and formation of micronuclei

Note: Chemical structures of ICG-001 and PRI-724 look very close

C#CCN[C@@H]1CCC2=CC=CC=C21

72 ml/min/kg for 250 μg/kg and 500 μg/kg in mice

Cytochalasin C K-0518) 3 nM in BF-227 (KdCytochalasin C is a cell permeable fungal toxin and induces the formation of nuclear rodlets. Cytochalasin C is 10 times less toxic in mice than is cytochalasin D. Product information CAS Number: 22144 76 9 Molecular Weight: 507. 62 Formula: C30H37NO6 Chemical Name: (3S,3aR,6S,6aR,10S,12R,15R,15aR) 3 benzyl 3a,6a dihydrogenio 6,12 dihydroxy 4,5,10,12 tetramethyl 1,11 dioxo 1H,2H,3H,3aH,6H,6aH,9H,10H,11H,12H,15H cycloundeca[e]isoindol 15 yl acetate