InChiKey: ANEBWFXPVPTEET-UHFFFAOYSA-N
Imatinib inhibits the SLF-dependent activation of wild-type c-kit kinase activity with a IC50 for these effects of approximately 0
ClH/c1-4-5-6-7-17-8-10-18(11-9-17)21-12-19-14-30(27(33)29-25(19)36-21)23-13-20(31)22(35-23)15-34-26(32)24(28)16(2)3
Epub 2013 Jun 25
BAY-985 is a potent and highly selective TBK1/IKKε inhibitor
PAT-1251 de dipotassium InChiKey: ANEBWFXPVPTEET-UHFFFAOYSA-NPAT 1251 is a potent, selective and oral lysyl oxidase like 2 (LOXL2) inhibitor, with IC50s of 0. 71 and 1. 17 M for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0. 10, 0. 12, and 0. 16 M, respectively); PAT 1251 is used in the research of fibrotic diseases. Product information CAS Number: 2007885 39 2 Molecular Weight: 399. 34 Formula: C18H17F4N3O3 Chemical Name: (3R,4R) 1 (3 {[4 (aminomethyl) 6