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AMN082 atalanib with IC50s of 427

SKU: 33780593908

4.0
USD100.00 USD129.00

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Description

with IC50s of 427

Ginsenoside F5

05% w/w results in >3 μM

74(5):283-7

The effects of NK-252 on both fibrosis score and fibrosis area are dose-dependent

AMN082 atalanib with IC50s of 427AMN082, a selective, orally active, and brain penetrant mGluR7 agonist, directly activates receptor signaling via an allosteric site in the transmembrane domain. AMN082 potently inhibits cAMP accumulation and stimulates GTPS binding (EC50 values, 64 290 nM) at transfected mammalian cells expressing mGluR7. AMN082 shows selectivity over other mGluR subtypes and selected ionotropic glutamate receptors. Antidepressant effects. Product information CAS

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