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[Epub ahead of print] PubMed PMID: 24817629
Constitutive activation of IkappaB kinase alpha and NF-kappaB in prostate cancer cells is inhibited by ibuprofen
hepatic (HepG2) and monocytic (THP-1) cell assays
Am J Nephrol
At 180 min after 99mTc-MIBI injection
UK-101 N-161 trifluoroacetate salt [Epub ahead of print] PubMedUK 101 is a potent and selective immunoproteasome 1i (LMP2) inhibitor with an IC50 value of 104 nM, displays 144 and 10 fold selectivity over 1c (IC50=15 M) and 5 subunit (IC50=1 M), respectivey. UK 101 induces cell apoptosis and can be used for the study of prostate cancer. Product information CAS Number: 1000313 40 5 Molecular Weight: 484. 74 Formula: C25H48N2O5Si Chemical Name: N [(1S) 1 {[(2S) 1 [(2S) 2 {[(tert butyldimethylsilyl)oxy]methyl}oxiran
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