CHMFL-EGFR-202 Size:Contact [email protected] for quotation InChi: InChI=1S/C24H21N5O2/c30-23-21(22(24(31)27-23)26-17-7-2-1-3-8-17)19-15-29(20-10-5-4-9-18(19)20)13-6-12-28-14-11-25-16-28/h1-5

InChi: InChI=1S/C24H21N5O2/c30-23-21(22(24(31)27-23)26-17-7-2-1-3-8-17)19-15-29(20-10-5-4-9-18(19)20)13-6-12-28-14-11-25-16-28/h1-5

MDL 28170 is a calpain inhibitor that protects against cortical neuronal damage even if the treatment is delayed until 3 h after reperfusion

95(1):99-109

Jatrorrhizine chloride is a potent and orally active inhibitor of AChE (IC50=872 nM) over >115-fold selectivity for BuChE

The total area of lipid droplets is far less than 25% of mean section of hepatocytes

CHMFL-EGFR-202 Size:Contact [email protected] for quotation InChi: InChI=1S/C24H21N5O2/c30-23-21(22(24(31)27-23)26-17-7-2-1-3-8-17)19-15-29(20-10-5-4-9-18(19)20)13-6-12-28-14-11-25-16-28/h1-5CHMFL EGFR 202 is a potent, irreversible inhibitor of epidermal growth factor receptor (EGFR) mutant kinase, with IC50s of 5. 3 nM and 8. 3 nM for drug resistant mutant EGFR T790M and WT EGFR kinases, respectively. CHMFL EGFR 202 exhibits 10 fold selectivity for EGFR L858R T790M against the EGFR wild type in cells. CHMFL EGFR 202 adopts a covalent DFG in C helix out inactive binding conformation with EGFR, with strong antiproliferative effects against