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BAY 87-2243 - Hypoxia-inducible Factor-1 (HIF-1) Inhibitor. CAS# 1227158-85-1 60069 Molecular Weight: 328

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Description

Molecular Weight: 328

PFI-2 has been shown to bind to SETD7 by ITC (Kd=18nM)

EPZ015666 was dosed to MCL (Z-138

GLPG0634 dose-dependently inhibits the differentiation of Th2 cells mediated by IL-4

5 μM and 0

BAY 87-2243 - Hypoxia-inducible Factor-1 (HIF-1) Inhibitor. CAS# 1227158-85-1 60069 Molecular Weight: 328BAY 87 2243, CAS No. 1227158 85 1, is a highly potent and selective inhibitor of hypoxia induced gene activation, which has antitumor activities by inhibition of mitochondrial complex I. BAY 87 2243 mproves local tumor control after fractionated irradiation in a schedule dependent manner in head and neck human xenografts. BAY 87 2243 markedly decreased nuclear HIF 1 expression and pimonidazole hypoxic fraction already after 3 days of drug treatment.

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