PJ34 - CAS# 344458-19-1 e O-desmethyl Mebeverine acid 5-difluorophenyl)sulfonyl)benzyl)imidazo[1

5-difluorophenyl)sulfonyl)benzyl)imidazo[1

Granuloma faciale successfully treated with ingenol mebutate

InChi: InChI=1S/C12H8N4O6S/c13-23(21

NSC59984 as a promising lead compound for anticancer therapy that acts by targeting GOF-mutant p53 and stimulates p73 to restore the p53 pathway signaling

It belongs to a class of antiplatelet named glycoprotein IIb/IIIa inhibitors

PJ34 - CAS# 344458-19-1 e O-desmethyl Mebeverine acid 5-difluorophenyl)sulfonyl)benzyl)imidazo[1PJ 34 is a novel and potent PARP 1 inhibitor with potential anticancer activity. PJ34 has a high affinity for PARP 1 (IC(50) = 20 nM). PJ 34 inhibits PARP 1 expression and ERK phosphorylation in glioma conditioned brain microvascular endothelial cells. PJ 34 reduces mesenteric vascular injury induced by experimental cardiopulmonary bypass with cardiac arrest. PJ 34 reduce cell inflammation and damage that follow PARP 1 overexpression. PJ 34 negatively