Human TROP2 Cell Lines & Culture Kits Jul 2008] Swissprot No O43561

Jul 2008] Swissprot No O43561 Gene Accession 27040 WB Predicted band size 28 kDa WB Positive control WB Recommended dilution 500-2000 IHC predicted cell location Predicted cell location: Cytoplasm IHC positive control Positive control: Human tonsil IHC Recommed dilution Recommended dilution: 50-100 Storage

This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins

whose members function as regulators of the cell cycle

Specific anti-human IgG antibodies are precoated on a high-affinity ELISA plate

Human Activin A freeze-dried standard

Human TROP2 Cell Lines & Culture Kits Jul 2008] Swissprot No O43561TROP 2 is a cell surface glycoprotein highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors. The human TROP 2 protein is composed of a putative 26 amino acid (aa) signal sequence, a 248 aa extracellular domain, a 23 aa transmembrane region and a 26 aa cytoplasmic domain. It is able to transduce an intracellular calcium signal with adhesive functions and probably plays a role in tumor