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InChiKey: PJJJBBJSCAKJQF-UHFFFAOYSA-N
InChiKey: CDOSHBSSFJOMGT-UHFFFAOYSA-N
α5β2γ2 and 0
and 15 mg/kg/day shows anticholinergic effects at high levels (dryness of mucosae
with IC50 of 2
ORM-15341 erine metabolite O-desmethyl Mebeverine acid InChiKey: PJJJBBJSCAKJQF-UHFFFAOYSA-NORM 15341 is a potent and full antagonist for human AR (hAR) with IC50 values of 38 nM as shown by transactivation assays in AR HEK293 cells stably expressing full length hAR and an androgen responsive luciferase reporter gene construct. IC50 value: 38 nMTarget: androgen receptorin vitro: In competitive AR binding assays, the inhibition constant (Ki) values of ORM 15341 was 8 nM. ORM 15341 functions as a full antagonist for all tested mutant ARs ,
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