HPK1-IN-3 Catalog No.:M16248-C Smiles: CC[C@@]12CC(=C3NC4=CC=CC=C4[C@]43CCN(CC=C1)[C@H]42)C(=O)OC

Smiles: CC[C@@]12CC(=C3NC4=CC=CC=C4[C@]43CCN(CC=C1)[C@H]42)C(=O)OC

Chemical Name: 6-nitro-1-benzothiophene-1

Proteasome inhibitors: recent advances and new perspectives in medicinal chemistry

InChi: InChI=1S/C22H23ClN2O8/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8

Sodium glycochenodeoxycholate

HPK1-IN-3 Catalog No.:M16248-C Smiles: CC[C@@]12CC(=C3NC4=CC=CC=C4[C@]43CCN(CC=C1)[C@H]42)C(=O)OCHPK1 IN 3 is a potent and selective ATP competitive hematopoietic progenitor kinase 1 (HPK1; MAP4K1) inhibitor with an IC50 of 0. 25 nM. HPK1 IN 3 has IL 2 cellular potency with an EC50 of 108 nM in human peripheral blood mononuclear cells (PBMCs). Product information Molecular Weight: 490. 45 Formula: C23H22F4N6O2 Chemical Name: 4 ((2 fluoro 6 (trifluoromethyl)phenyl)amino) 2 ((6 methoxy 2 methyl 1, 2, 3, 4 tetrahydroisoquinolin 7 yl)amino)pyrimidine