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VER-49009 Size:Solid 10 mg Diosmin exhibits anti-hyperlipidemic effects in

SKU: 16136137047

4.0
USD95.00 USD120.00

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Description

Diosmin exhibits anti-hyperlipidemic effects in isoproterenol induced myocardial infarcted rats

Solubility: DMSO : 25 mg/mL (99

176-fold more selective for class I HDACs

10 µM) suppresses 2

and SW480 cancer cells with IC50 values of 0

VER-49009 Size:Solid 10 mg Diosmin exhibits anti-hyperlipidemic effects inVER 49009 is a potent HSP90 inhibitor. VER 49009 inhibits Hsp90 with an IC50 value of 47 nM. VER 49009 produces a cellular antiproliferative GI50 value of 685 nM when tested against a human cancer cell line panel. Consistent with inhibition of Hsp90, VER 49009 induces the expression of Hsp27 and Hsp72 while reducing the client proteins C RAF, B RAF, survivin, and PRMT5, causing cell cycle arrest and apoptosis. Product information CAS Number: 558640 51

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